Robust Performance of Potentially Functional SNPs in Machine Learning Models for the Prediction of Atorvastatin-Induced Myalgia

Statins can cause muscle symptoms resulting in poor adherence to therapy and increased cardiovascular risk. We hypothesize that combinations of potentially functional SNPs (pfSNPs), rather than individual SNPs, better predict myalgia in patients on atorvastatin. This study assesses the value of pote...

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Detalles Bibliográficos
Autores principales: Ooi, Brandon N. S., Raechell, Ying, Ariel F., Koh, Yong Zher, Jin, Yu, Yee, Sherman W. L., Lee, Justin H. S., Chong, Samuel S., Tan, Jack W. C., Liu, Jianjun, Lee, Caroline G., Drum, Chester L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100589/
https://www.ncbi.nlm.nih.gov/pubmed/33967749
http://dx.doi.org/10.3389/fphar.2021.605764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100589/
https://www.ncbi.nlm.nih.gov/pubmed/33967749
http://dx.doi.org/10.3389/fphar.2021.605764

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