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Robust Performance of Potentially Functional SNPs in Machine Learning Models for the Prediction of Atorvastatin-Induced Myalgia
Statins can cause muscle symptoms resulting in poor adherence to therapy and increased cardiovascular risk. We hypothesize that combinations of potentially functional SNPs (pfSNPs), rather than individual SNPs, better predict myalgia in patients on atorvastatin. This study assesses the value of pote...
Autores principales: | Ooi, Brandon N. S., Raechell, Ying, Ariel F., Koh, Yong Zher, Jin, Yu, Yee, Sherman W. L., Lee, Justin H. S., Chong, Samuel S., Tan, Jack W. C., Liu, Jianjun, Lee, Caroline G., Drum, Chester L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100589/ https://www.ncbi.nlm.nih.gov/pubmed/33967749 http://dx.doi.org/10.3389/fphar.2021.605764 |
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