Inhibition of Small-Conductance, Ca(2+)-Activated K(+) Current by Ondansetron

Background: Small-conductance Ca(2+)-activated K(+) channels (SK channels) have been proposed as antiarrhythmic targets for the treatment of atrial fibrillation. We previously demonstrated that the 5-HT(3) receptor antagonist ondansetron inhibits heterologously expressed, human SK2 (hSK2) currents a...

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Detalles Bibliográficos
Autores principales: Guo, Shuai, Chen, Zhenhui, Chen, Peng-Sheng, Rubart, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100601/
https://www.ncbi.nlm.nih.gov/pubmed/33967791
http://dx.doi.org/10.3389/fphar.2021.651267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100601/
https://www.ncbi.nlm.nih.gov/pubmed/33967791
http://dx.doi.org/10.3389/fphar.2021.651267

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