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Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson’s Disease

Real-world healthcare data hold the potential to identify therapeutic solutions for progressive diseases by efficiently pinpointing safe and efficacious repurposing drug candidates. This approach circumvents key early clinical development challenges, particularly relevant for neurological diseases,...

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Detalles Bibliográficos
Autores principales: Laifenfeld, Daphna, Yanover, Chen, Ozery-Flato, Michal, Shaham, Oded, Rosen-Zvi, Michal, Lev, Nirit, Goldschmidt, Yaara, Grossman, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100658/
https://www.ncbi.nlm.nih.gov/pubmed/33967767
http://dx.doi.org/10.3389/fphar.2021.631584