One-Pot Synthesis of (Z)-β-Halovinyl Ketones via the Cascade of Sonogashira Coupling and Hydrohalogenation

Herein, we report an efficient method for the synthesis of (Z)-β-halovinyl ketones through a one-pot Sonogashira coupling and hydrohalogenation reaction promoted by palladium-copper catalyst and Brønsted acid. The ynone intermediates are generated in situ from readily available acid chlorides and te...

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Detalles Bibliográficos
Autores principales: Chen, Fa-Jie, Hua, Zhenguo, Chen, Jianhui, Chen, Jiajia, Lee, Daesung, Xia, Yuanzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100659/
https://www.ncbi.nlm.nih.gov/pubmed/33968892
http://dx.doi.org/10.3389/fchem.2020.621545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100659/
https://www.ncbi.nlm.nih.gov/pubmed/33968892
http://dx.doi.org/10.3389/fchem.2020.621545

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