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One-Pot Synthesis of (Z)-β-Halovinyl Ketones via the Cascade of Sonogashira Coupling and Hydrohalogenation

Herein, we report an efficient method for the synthesis of (Z)-β-halovinyl ketones through a one-pot Sonogashira coupling and hydrohalogenation reaction promoted by palladium-copper catalyst and Brønsted acid. The ynone intermediates are generated in situ from readily available acid chlorides and te...

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Detalles Bibliográficos
Autores principales:	Chen, Fa-Jie, Hua, Zhenguo, Chen, Jianhui, Chen, Jiajia, Lee, Daesung, Xia, Yuanzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100659/ https://www.ncbi.nlm.nih.gov/pubmed/33968892 http://dx.doi.org/10.3389/fchem.2020.621545

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