Targeting Gremlin 1 Prevents Intestinal Fibrosis Progression by Inhibiting the Fatty Acid Oxidation of Fibroblast Cells

Intestinal fibrosis is a consequence of continuous inflammatory responses that negatively affect the quality of life of patients. By screening altered proteomic profiles of mouse fibrotic colon tissues, we identified that GREM1 was dramatically upregulated in comparison to that in normal tissues. Fu...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zeng, Qi-Shan, Zou, Min, Zeng, Jian, Nie, Jiao, Chen, DongFeng, Gan, Hua-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100665/
https://www.ncbi.nlm.nih.gov/pubmed/33967807
http://dx.doi.org/10.3389/fphar.2021.663774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100665/
https://www.ncbi.nlm.nih.gov/pubmed/33967807
http://dx.doi.org/10.3389/fphar.2021.663774

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