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BTLA Expression and Function Are Impaired on SLE B Cells

B- and T-lymphocyte attenuator (BTLA/CD272) is an inhibitory checkpoint molecule expressed on T and B cells. Prior studies reported defective function of BTLA by T cells in patients with systemic lupus erythematosus (SLE), whereas nothing is known about its role on B cells in SLE, a disease with var...

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Detalles Bibliográficos
Autores principales: Wiedemann, Annika, Lettau, Marie, Weißenberg, Sarah Y., Stefanski, Ana-Luisa, Schrezenmeier, Eva-Vanessa, Rincon-Arevalo, Hector, Reiter, Karin, Alexander, Tobias, Hiepe, Falk, Lino, Andreia C., Dörner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100666/
https://www.ncbi.nlm.nih.gov/pubmed/33968071
http://dx.doi.org/10.3389/fimmu.2021.667991