RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice

The present studies evaluate the in vivo prophylactic radioprotective effects of 1-bromoacetyl-3, 3-dinitroazetidine (RRx-001), a phase III anticancer agent that inhibits c-myc and downregulates CD-47, after total body irradiation (TBI), in lethally and sublethally irradiated CD2F1 male mice. A sing...

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Detalles Bibliográficos
Autores principales: Jurgensen, Kimberly J., Skinner, William K. J., Oronsky, Bryan, Abrouk, Nacer D., Graff, Andrew E., Landes, Reid D., Culp, William E., Summers, Thomas A., Cary, Lynnette H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100686/
https://www.ncbi.nlm.nih.gov/pubmed/33967816
http://dx.doi.org/10.3389/fphar.2021.676396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100686/
https://www.ncbi.nlm.nih.gov/pubmed/33967816
http://dx.doi.org/10.3389/fphar.2021.676396

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