The m6A methyltransferase METTL3 regulates autophagy and sensitivity to cisplatin by targeting ATG5 in seminoma

BACKGROUND: Our previous work shows Autophagy enhanced resistance to cisplatin in seminoma. The expression of the N6-methyladenosine (m6A) methyltransferases METTL3 was significantly increased in the cisplatin-resistant TCam-2 cell line of seminoma. We aimed to investigate the role of m6A methylatio...

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Detalles Bibliográficos
Autores principales: Chen, Hanfei, Xiang, Yali, Yin, Yinghao, Peng, Jingxuan, Peng, Dongyi, Li, Dongjie, Kitazawa, Riko, Tang, Yuxin, Yang, Jianfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100844/
https://www.ncbi.nlm.nih.gov/pubmed/33968659
http://dx.doi.org/10.21037/tau-20-1411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8100844/
https://www.ncbi.nlm.nih.gov/pubmed/33968659
http://dx.doi.org/10.21037/tau-20-1411

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