Cargando…
Investigations into the synthesis of a nucleotide dimer via mechanochemical phosphoramidite chemistry
Liquid-assisted mechanochemistry as a versatile approach for the coupling of a nucleoside phosphoramidite with a 5′-OH partially protected nucleoside has been investigated. Noted advantages over reported methods were a simplified reaction protocol, a drastic reduction in the use of toxic solvents, t...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101013/ https://www.ncbi.nlm.nih.gov/pubmed/34035937 http://dx.doi.org/10.1098/rsos.201703 |