Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion

BACKGROUND: Chronic cerebral hypoperfusion (CCH) is the leading cause of cerebral small vessel disease (CSVD). CCH is strongly associated with blood–brain barrier (BBB) dysfunction and white matter lesions (WMLs) in CSVD. However, the effects of CCH on BBB integrity and components and the cellular a...

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Detalles Bibliográficos
Autores principales: Sun, Zhengyu, Gao, Chenhao, Gao, Dandan, Sun, Ruihua, Li, Wei, Wang, Fengyu, Wang, Yanliang, Cao, Huixia, Zhou, Guoyu, Zhang, Jiewen, Shang, Junkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101037/
https://www.ncbi.nlm.nih.gov/pubmed/33952281
http://dx.doi.org/10.1186/s12987-021-00255-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101037/
https://www.ncbi.nlm.nih.gov/pubmed/33952281
http://dx.doi.org/10.1186/s12987-021-00255-2

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