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Lotus-root-shaped cell-encapsulated construct as a retrieval graft for long-term transplantation of human iPSC-derived β-cells

Cell therapy using human-stem-cell-derived pancreatic beta cells (hSC-βs) is a potential treatment method for type 1 diabetes mellitus (T1D). For therapeutic safety, hSC-βs need encapsulation in grafts that are scalable and retrievable. In this study, we developed a lotus-root-shaped cell-encapsulat...

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Detalles Bibliográficos
Autores principales: Ozawa, Fumisato, Nagata, Shogo, Oda, Haruka, Yabe, Shigeharu G., Okochi, Hitoshi, Takeuchi, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101052/
https://www.ncbi.nlm.nih.gov/pubmed/33997668
http://dx.doi.org/10.1016/j.isci.2021.102309