Complex Landscape of Alternative Splicing in Myeloid Neoplasms

Myeloid neoplasms are characterized by frequent mutations in at least seven components of the spliceosome that have distinct roles in the process of pre-mRNA splicing. Hotspot mutations in SF3B1, SRSF2, U2AF1 and loss of function mutations in ZRSR2 have revealed widely different aberrant splicing si...

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Detalles Bibliográficos
Autores principales: Hershberger, Courtney E., Moyer, Devlin C., Adema, Vera, Kerr, Cassandra M., Walter, Wencke, Hutter, Stephan, Meggendorfer, Manja, Baer, Constance, Kern, Wolfgang, Nadarajah, Niroshan, Twardziok, Sven, Sekeres, Mikkael A., Haferlach, Claudia, Haferlach, Torsten, Maciejewski, Jaroslaw P., Padgett, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101081/
https://www.ncbi.nlm.nih.gov/pubmed/32753690
http://dx.doi.org/10.1038/s41375-020-1002-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101081/
https://www.ncbi.nlm.nih.gov/pubmed/32753690
http://dx.doi.org/10.1038/s41375-020-1002-y

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