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Current views on the genetic landscape and management of variant acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is characterized by the accumulation of promyelocytes in bone marrow. More than 95% of patients with this disease belong to typical APL, which express PML-RARA and are sensitive to differentiation induction therapy containing all-trans retinoic acid (ATRA) and arse...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Sun, Jiewen, Yu, Wenjuan, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101136/
https://www.ncbi.nlm.nih.gov/pubmed/33957999
http://dx.doi.org/10.1186/s40364-021-00284-x