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Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons

BACKGROUND: Nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2)-induced oxidative stress, including the production of reactive oxygen species (ROS) and hydrogen peroxide, plays a pivotal role in neuropathic pain. Although the activation and plasma membrane translocation of protein kinase C...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Wu, Shinan, Wang, Junfei, Wang, Jianmei, Yan, Yi, Zhu, Mengye, Zhang, Daying, Jiang, Changyu, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101139/
https://www.ncbi.nlm.nih.gov/pubmed/33952299
http://dx.doi.org/10.1186/s12974-021-02155-6