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Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells
BACKGROUND: Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine with both anti-tumorigenic and pro-tumorigenic activity, affecting tumor cell biology, the balance between cell survival and death. The final effect of TNFα is dependent on the type of malignant cells, with the potential to arr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101174/ https://www.ncbi.nlm.nih.gov/pubmed/33957885 http://dx.doi.org/10.1186/s12885-021-08237-1 |