Systematic interrogation of mutation groupings reveals divergent downstream expression programs within key cancer genes

BACKGROUND: Genes implicated in tumorigenesis often exhibit diverse sets of genomic variants in the tumor cohorts within which they are frequently mutated. For many genes, neither the transcriptomic effects of these variants nor their relationship to one another in cancer processes have been well-ch...

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Detalles Bibliográficos
Autores principales: Grzadkowski, Michal R., Holly, Hannah D., Somers, Julia, Demir, Emek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101181/
https://www.ncbi.nlm.nih.gov/pubmed/33957863
http://dx.doi.org/10.1186/s12859-021-04147-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101181/
https://www.ncbi.nlm.nih.gov/pubmed/33957863
http://dx.doi.org/10.1186/s12859-021-04147-y

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