Tejaas: reverse regression increases power for detecting trans-eQTLs

Trans-acting expression quantitative trait loci (trans-eQTLs) account for ≥70% expression heritability and could therefore facilitate uncovering mechanisms underlying the origination of complex diseases. Identifying trans-eQTLs is challenging because of small effect sizes, tissue specificity, and a...

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Detalles Bibliográficos
Autores principales: Banerjee, Saikat, Simonetti, Franco L., Detrois, Kira E., Kaphle, Anubhav, Mitra, Raktim, Nagial, Rahul, Söding, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101255/
https://www.ncbi.nlm.nih.gov/pubmed/33957961
http://dx.doi.org/10.1186/s13059-021-02361-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101255/
https://www.ncbi.nlm.nih.gov/pubmed/33957961
http://dx.doi.org/10.1186/s13059-021-02361-8

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