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Tejaas: reverse regression increases power for detecting trans-eQTLs

Trans-acting expression quantitative trait loci (trans-eQTLs) account for ≥70% expression heritability and could therefore facilitate uncovering mechanisms underlying the origination of complex diseases. Identifying trans-eQTLs is challenging because of small effect sizes, tissue specificity, and a...

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Detalles Bibliográficos
Autores principales:	Banerjee, Saikat, Simonetti, Franco L., Detrois, Kira E., Kaphle, Anubhav, Mitra, Raktim, Nagial, Rahul, Söding, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101255/ https://www.ncbi.nlm.nih.gov/pubmed/33957961 http://dx.doi.org/10.1186/s13059-021-02361-8

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