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Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence

The notion that in diabetes pancreatic β-cells express endoplasmic reticulum (ER) stress markers indicative of increased unfolded protein response (UPR) signaling is no longer in doubt. However, what remains controversial is whether this increase in ER stress response actually contributes importantl...

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Detalles Bibliográficos
Autores principales: Shrestha, Neha, De Franco, Elisa, Arvan, Peter, Cnop, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101261/
https://www.ncbi.nlm.nih.gov/pubmed/33967960
http://dx.doi.org/10.3389/fendo.2021.650158