Cargando…
Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence
The notion that in diabetes pancreatic β-cells express endoplasmic reticulum (ER) stress markers indicative of increased unfolded protein response (UPR) signaling is no longer in doubt. However, what remains controversial is whether this increase in ER stress response actually contributes importantl...
Autores principales: | Shrestha, Neha, De Franco, Elisa, Arvan, Peter, Cnop, Miriam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101261/ https://www.ncbi.nlm.nih.gov/pubmed/33967960 http://dx.doi.org/10.3389/fendo.2021.650158 |
Ejemplares similares
-
Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes
por: Bugliani, M., et al.
Publicado: (2019) -
Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes
por: Marré, Meghan L., et al.
Publicado: (2017) -
Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells
por: Cnop, Miriam, et al.
Publicado: (2017) -
Endoplasmic reticulum stress response and transcriptional reprogramming
por: Zhang, Kezhong
Publicado: (2015) -
Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells
por: Snyder, Jarin T., et al.
Publicado: (2021)