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On-demand synthesis of phosphoramidites

Automated chemical synthesis of oligonucleotides is of fundamental importance for the production of primers for the polymerase chain reaction (PCR), for oligonucleotide-based drugs, and for numerous other medical and biotechnological applications. The highly optimised automised chemical oligonucleot...

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Detalles Bibliográficos
Autores principales: Sandahl, Alexander F., Nguyen, Thuy J. D., Hansen, Rikke A., Johansen, Martin B., Skrydstrup, Troels, Gothelf, Kurt V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101336/
https://www.ncbi.nlm.nih.gov/pubmed/33958587
http://dx.doi.org/10.1038/s41467-021-22945-z