The IgG3 subclass of β1-adrenergic receptor autoantibodies is an endogenous biaser of β1AR signaling

Dysregulation of immune responses has been linked to the generation of immunoglobulin G (IgG) autoantibodies that target human β1ARs and contribute to deleterious cardiac outcomes. Given the benefits of β-blockers observed in patients harboring the IgG3 subclass of autoantibodies, we investigated th...

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Detalles Bibliográficos
Autores principales: Mohan, Maradumane L., Nagatomo, Yuji, Saha, Prasenjit Prasad, Mukherjee, Sromona D., Engelman, Timothy, Morales, Rommel, Hazen, Stanley L., Tang, W. H. Wilson, Prasad, Sathyamangla V. Naga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101462/
https://www.ncbi.nlm.nih.gov/pubmed/33534612
http://dx.doi.org/10.1091/mbc.E20-06-0394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101462/
https://www.ncbi.nlm.nih.gov/pubmed/33534612
http://dx.doi.org/10.1091/mbc.E20-06-0394

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