Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration

The asymmetric distribution of microtubule (MT) dynamics in migrating cells is important for cell polarization, yet the underlying regulatory mechanisms remain underexplored. Here, we addressed this question by studying the role of the MT depolymerase, MCAK (mitotic centromere-associated kinesin), i...

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Detalles Bibliográficos
Autores principales: Zong, Hailing, Hazelbaker, Mark, Moe, Christina, Ems-McClung, Stephanie C., Hu, Ke, Walczak, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101467/
https://www.ncbi.nlm.nih.gov/pubmed/33566676
http://dx.doi.org/10.1091/mbc.E20-05-0301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101467/
https://www.ncbi.nlm.nih.gov/pubmed/33566676
http://dx.doi.org/10.1091/mbc.E20-05-0301

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