A phase I, single and continuous dose administration study on the safety, tolerability, and pharmacokinetics of neorudin, a novel recombinant anticoagulant protein, in healthy subjects

The aim of this study was to evaluate the tolerability, safety, and pharmacokinetics of single and continuous dose administration of recombinant neorudin (EPR‐hirudin, EH) by intravenous administration in healthy subjects, and to provide a safe dosage range for phase II clinical research. Forty‐four...

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Detalles Bibliográficos
Autores principales: Liu, Yubin, Wang, Meixia, Dong, Xiaona, He, Jia, Zhang, Lin, Zhou, Ying, Xia, Xia, Dou, Guifang, Wu, Chu‐tse, Jin, Jide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101608/
https://www.ncbi.nlm.nih.gov/pubmed/33957018
http://dx.doi.org/10.1002/prp2.785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101608/
https://www.ncbi.nlm.nih.gov/pubmed/33957018
http://dx.doi.org/10.1002/prp2.785

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