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Effect of CHRFAM7A Δ2bp gene variant on secondary inflammation after spinal cord injury

The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impact the anti-inflammatory function. We studied 45 spinal...

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Detalles Bibliográficos
Autores principales: Lin, Mingkuan, Huang, Wan, Kabbani, Nadine, Theiss, Mark M., Hamilton, John F., Ecklund, James M., Conley, Yvette P., Vodovotz, Yoram, Brienza, David, Wagner, Amy K., Robbins, Emily, Sowa, Gwendolyn A., Lipsky, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101719/
https://www.ncbi.nlm.nih.gov/pubmed/33956875
http://dx.doi.org/10.1371/journal.pone.0251110