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Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis

The ESCRT pathway is evolutionarily conserved across eukaryotes and plays key roles in a variety of membrane remodeling processes. A new Drosophila mutant recovered in our forward genetic screens for synaptic transmission mutants mapped to the vps24 gene encoding a subunit of the ESCRT-III complex....

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Detalles Bibliográficos
Autores principales: Florian, Jonathan R., DeMatte, Samuel J., Sweeder, Devon M., Ordway, Richard W., Kawasaki, Fumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101729/
https://www.ncbi.nlm.nih.gov/pubmed/33956855
http://dx.doi.org/10.1371/journal.pone.0251184