Cargando…

Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis

The ESCRT pathway is evolutionarily conserved across eukaryotes and plays key roles in a variety of membrane remodeling processes. A new Drosophila mutant recovered in our forward genetic screens for synaptic transmission mutants mapped to the vps24 gene encoding a subunit of the ESCRT-III complex....

Descripción completa

Detalles Bibliográficos
Autores principales:	Florian, Jonathan R., DeMatte, Samuel J., Sweeder, Devon M., Ordway, Richard W., Kawasaki, Fumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101729/ https://www.ncbi.nlm.nih.gov/pubmed/33956855 http://dx.doi.org/10.1371/journal.pone.0251184

Ejemplares similares

Design principles of the ESCRT-III Vps24-Vps2 module
por: Banjade, Sudeep, et al.
Publicado: (2021)

Structure and assembly of ESCRT-III helical Vps24 filaments
por: Huber, Stefan T., et al.
Publicado: (2020)

Assembly of the AAA ATPase Vps4 on ESCRT-III
por: Shestakova, Anna, et al.
Publicado: (2010)

Vps60 initiates alternative ESCRT-III filaments
por: Pfitzner, Anna-Katharina, et al.
Publicado: (2023)

Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD
por: Dubey, Sandeep Kumar, et al.
Publicado: (2022)

Asymmetric ring structure of Vps4 required for ESCRT-III disassembly
por: Caillat, Christophe, et al.
Publicado: (2015)

VPS4 triggers constriction and cleavage of ESCRT-III helical filaments
por: Maity, Sourav, et al.
Publicado: (2019)

ESCRT-III/Vps4 Controls Heterochromatin-Nuclear Envelope Attachments
por: Pieper, Gerard H., et al.
Publicado: (2020)

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation
por: Yang, Bei, et al.
Publicado: (2015)

Coevolution of Eukaryote-like Vps4 and ESCRT-III Subunits in the Asgard Archaea
por: Lu, Zhongyi, et al.
Publicado: (2020)

Physiological Involvement in pH Signaling of Vps24-mediated Recruitment of Aspergillus PalB Cysteine Protease to ESCRT-III
por: Rodríguez-Galán, Olga, et al.
Publicado: (2009)

Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes
por: Nickerson, Daniel P., et al.
Publicado: (2006)

Coordination of Substrate Binding and ATP Hydrolysis in Vps4-Mediated ESCRT-III Disassembly
por: Davies, Brian A., et al.
Publicado: (2010)

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
por: Adell, Manuel Alonso Y, et al.
Publicado: (2017)

ESCRTing proteasomes to the lysosome
por: Segev, Nava
Publicado: (2020)

Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II
por: Wernimont, Amy K, et al.
Publicado: (2004)

Interactome of the Plant-specific ESCRT-III Component AtVPS2.2 in Arabidopsis thaliana
por: Ibl, Verena, et al.
Publicado: (2011)

Structure and mechanism of the ESCRT pathway AAA+ ATPase Vps4
por: Han, Han, et al.
Publicado: (2019)

VPS37A directs ESCRT recruitment for phagophore closure
por: Takahashi, Yoshinori, et al.
Publicado: (2019)

Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
por: Vonk, Jan J., et al.
Publicado: (2017)

A Tripartite Synapse Model in Drosophila
por: Danjo, Rie, et al.
Publicado: (2011)

ESCRT-III and ER–PM contacts maintain lipid homeostasis
por: Jorgensen, Jeff R., et al.
Publicado: (2020)

Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation
por: Adell, Manuel Alonso Y, et al.
Publicado: (2014)

Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis
por: Mierzwa, Beata E., et al.
Publicado: (2017)

Vps27 recruits ESCRT machinery to endosomes during MVB sorting
por: Katzmann, David J., et al.
Publicado: (2003)

Dynamic Association of ESCRT-II Proteins with ESCRT-I and ESCRT-III Complexes during Phagocytosis of Entamoeba histolytica
por: Díaz-Hernández, Mitzi, et al.
Publicado: (2023)

Curcumin Prevents Formation of Polyglutamine Aggregates by Inhibiting Vps36, a Component of the ESCRT-II Complex
por: Verma, Meenakshi, et al.
Publicado: (2012)

The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets
por: Han, Han, et al.
Publicado: (2017)

The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division
por: Hurtig, Fredrik, et al.
Publicado: (2023)

Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome
por: Bilodeau, Patricia S., et al.
Publicado: (2003)

Cell layer-specific distribution of transiently expressed barley ESCRT-III component HvVPS60 in developing barley endosperm
por: Hilscher, Julia, et al.
Publicado: (2015)

Assembly and disassembly of the ESCRT-III membrane scission complex
por: Alonso Y Adell, Manuel, et al.
Publicado: (2011)

A Distinct Perisynaptic Glial Cell Type Forms Tripartite Neuromuscular Synapses in the Drosophila Adult
por: Strauss, Alexandra L., et al.
Publicado: (2015)

Genetic structure and evolution of the Vps25 family, a yeast ESCRT-II component
por: Slater, Ruth, et al.
Publicado: (2006)

ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins
por: Zhu, Lu, et al.
Publicado: (2017)

Abscission Is Regulated by the ESCRT-III Protein Shrub in Drosophila Germline Stem Cells
por: Matias, Neuza Reis, et al.
Publicado: (2015)

ESCRT-III has an escort
por: Leslie, Mitch
Publicado: (2011)

ESCRT-III gets the bends
por: Leslie, Mitch
Publicado: (2014)

Pkh1/2-dependent phosphorylation of Vps27 regulates ESCRT-I recruitment to endosomes
por: Morvan, Joëlle, et al.
Publicado: (2012)

The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei
por: Coyne, Alyssa N., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ko65fhaicr3hvlmsj5sjbviach