Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PD-L1 correlates weakly with RT-qPCR

Most lung cancer patients are diagnosed at an advanced stage, limiting their treatment options with very low response rate. Lung cancer is the most common cause of cancer death worldwide. Therapies that target driver gene mutations (e.g. EGFR, ALK, ROS1) and checkpoint inhibitors such anti-PD-1 and...

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Detalles Bibliográficos
Autores principales: Alwithenani, Akram, Bethune, Drew, Castonguay, Mathieu, Drucker, Arik, Flowerdew, Gordon, Forsythe, Marika, French, Daniel, Fris, John, Greer, Wenda, Henteleff, Harry, MacNeil, Mary, Marignani, Paola, Morzycki, Wojciech, Plourde, Madelaine, Snow, Stephanie, Marcato, Paola, Xu, Zhaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101740/
https://www.ncbi.nlm.nih.gov/pubmed/33956842
http://dx.doi.org/10.1371/journal.pone.0251080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8101740/
https://www.ncbi.nlm.nih.gov/pubmed/33956842
http://dx.doi.org/10.1371/journal.pone.0251080

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