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An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference
Several distinct activities and functions have been described for chromatin insulators, which separate genes along chromosomes into functional units. Here, we describe a novel mechanism of functional separation whereby an insulator prevents gene repression. When the homie insulator is deleted from t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102011/ https://www.ncbi.nlm.nih.gov/pubmed/33901190 http://dx.doi.org/10.1371/journal.pgen.1009536 |