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DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction

Diaphanous (DIAPH) three (DIAPH3) is a member of the formin proteins that have the capacity to nucleate and elongate actin filaments and, therefore, to remodel the cytoskeleton. DIAPH3 is essential for cytokinesis as its dysfunction impairs the contractile ring and produces multinucleated cells. Her...

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Detalles Bibliográficos
Autores principales: Lau, Eva On-Chai, Damiani, Devid, Chehade, Georges, Ruiz-Reig, Nuria, Saade, Rana, Jossin, Yves, Aittaleb, Mohamed, Schakman, Olivier, Tajeddine, Nicolas, Gailly, Philippe, Tissir, Fadel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102060/
https://www.ncbi.nlm.nih.gov/pubmed/33899739
http://dx.doi.org/10.7554/eLife.61974