Cargando…
DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
Diaphanous (DIAPH) three (DIAPH3) is a member of the formin proteins that have the capacity to nucleate and elongate actin filaments and, therefore, to remodel the cytoskeleton. DIAPH3 is essential for cytokinesis as its dysfunction impairs the contractile ring and produces multinucleated cells. Her...
Autores principales: | Lau, Eva On-Chai, Damiani, Devid, Chehade, Georges, Ruiz-Reig, Nuria, Saade, Rana, Jossin, Yves, Aittaleb, Mohamed, Schakman, Olivier, Tajeddine, Nicolas, Gailly, Philippe, Tissir, Fadel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102060/ https://www.ncbi.nlm.nih.gov/pubmed/33899739 http://dx.doi.org/10.7554/eLife.61974 |
Ejemplares similares
-
Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
por: Damiani, Devid, et al.
Publicado: (2016) -
KIF2A deficiency causes early-onset neurodegeneration
por: Ruiz-Reig, Nuria, et al.
Publicado: (2022) -
Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons
por: Ruiz-Reig, Nuria, et al.
Publicado: (2023) -
WNT signaling at the intersection between neurogenesis and brain tumorigenesis
por: Alkailani, Maisa I., et al.
Publicado: (2022) -
Neural progenitor fate decision defects, cortical hypoplasia and behavioral impairment in Celsr1-deficient mice
por: Boucherie, C, et al.
Publicado: (2018)