Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria

Translesion synthesis (TLS) is a highly conserved mutagenic DNA lesion tolerance pathway, which employs specialized, low-fidelity DNA polymerases to synthesize across lesions. Current models suggest that activity of these polymerases is predominantly associated with ongoing replication, functioning...

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Detalles Bibliográficos
Autores principales: Joseph, Asha Mary, Daw, Saheli, Sadhir, Ismath, Badrinarayanan, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102061/
https://www.ncbi.nlm.nih.gov/pubmed/33856342
http://dx.doi.org/10.7554/eLife.67552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102061/
https://www.ncbi.nlm.nih.gov/pubmed/33856342
http://dx.doi.org/10.7554/eLife.67552

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