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Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria
Translesion synthesis (TLS) is a highly conserved mutagenic DNA lesion tolerance pathway, which employs specialized, low-fidelity DNA polymerases to synthesize across lesions. Current models suggest that activity of these polymerases is predominantly associated with ongoing replication, functioning...
Autores principales: | Joseph, Asha Mary, Daw, Saheli, Sadhir, Ismath, Badrinarayanan, Anjana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102061/ https://www.ncbi.nlm.nih.gov/pubmed/33856342 http://dx.doi.org/10.7554/eLife.67552 |
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