Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells

Disruption of the circadian clock machinery in cancer cells is implicated in tumor malignancy. Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs are often characterized by high aldehyde dehydrogenase (ALDH)...

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Detalles Bibliográficos
Autores principales: Ogino, Takashi, Matsunaga, Naoya, Tanaka, Takahiro, Tanihara, Tomohito, Terajima, Hideki, Yoshitane, Hikari, Fukada, Yoshitaka, Tsuruta, Akito, Koyanagi, Satoru, Ohdo, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102063/
https://www.ncbi.nlm.nih.gov/pubmed/33890571
http://dx.doi.org/10.7554/eLife.66155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102063/
https://www.ncbi.nlm.nih.gov/pubmed/33890571
http://dx.doi.org/10.7554/eLife.66155

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