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Do caffeine and more selective adenosine A(2A) receptor antagonists protect against dopaminergic neurodegeneration in Parkinson’s disease?

The adenosine A(2A) receptor is a major target of caffeine, the most widely used psychoactive substance worldwide. Large epidemiological studies have long shown caffeine consumption is a strong inverse predictor of Parkinson’s disease (PD). In this review, we first examine the epidemiology of caffei...

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Detalles Bibliográficos
Autores principales: Chen, Jiang-Fan, Schwarzschild, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102090/
https://www.ncbi.nlm.nih.gov/pubmed/33349580
http://dx.doi.org/10.1016/j.parkreldis.2020.10.024