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Do caffeine and more selective adenosine A(2A) receptor antagonists protect against dopaminergic neurodegeneration in Parkinson’s disease?
The adenosine A(2A) receptor is a major target of caffeine, the most widely used psychoactive substance worldwide. Large epidemiological studies have long shown caffeine consumption is a strong inverse predictor of Parkinson’s disease (PD). In this review, we first examine the epidemiology of caffei...
Autores principales: | Chen, Jiang-Fan, Schwarzschild, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102090/ https://www.ncbi.nlm.nih.gov/pubmed/33349580 http://dx.doi.org/10.1016/j.parkreldis.2020.10.024 |
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