Clinical impact of panel-based error-corrected next generation sequencing versus flow cytometry to detect measurable residual disease (MRD) in acute myeloid leukemia (AML)

We accrued 201 patients of adult AML treated with conventional therapy, in morphological remission, and evaluated MRD using sensitive error-corrected next generation sequencing (NGS-MRD) and multiparameter flow cytometry (FCM-MRD) at the end of induction (PI) and consolidation (PC). Nearly 71% of pa...

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Detalles Bibliográficos
Autores principales: Patkar, Nikhil, Kakirde, Chinmayee, Shaikh, Anam Fatima, Salve, Rakhi, Bhanshe, Prasanna, Chatterjee, Gaurav, Rajpal, Sweta, Joshi, Swapnali, Chaudhary, Shruti, Kodgule, Rohan, Ghoghale, Sitaram, Deshpande, Nilesh, Shetty, Dhanalaxmi, Khizer, Syed Hasan, Jain, Hasmukh, Bagal, Bhausaheb, Menon, Hari, Khattry, Navin, Sengar, Manju, Tembhare, Prashant, Subramanian, Papagudi, Gujral, Sumeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102181/
https://www.ncbi.nlm.nih.gov/pubmed/33558666
http://dx.doi.org/10.1038/s41375-021-01131-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102181/
https://www.ncbi.nlm.nih.gov/pubmed/33558666
http://dx.doi.org/10.1038/s41375-021-01131-6

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