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IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction—a retrospective propensity score analysis

Clonal hematopoiesis of indeterminate potential (CHIP) is linked to leukemia gene mutations and associates with an increased risk for coronary artery disease and poor prognosis in ischemic cardiomyopathy. Two recurrently mutated genes in CHIP and adult acute myeloid leukemia (AML) encode for isocitr...

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Detalles Bibliográficos
Autores principales: Kattih, Badder, Shirvani, Amir, Klement, Piroska, Garrido, Abel Martin, Gabdoulline, Razif, Liebich, Alessandro, Brandes, Maximilian, Chaturvedi, Anuhar, Seeger, Timon, Thol, Felicitas, Göhring, Gudrun, Schlegelberger, Brigitte, Geffers, Robert, John, David, Bavendiek, Udo, Bauersachs, Johann, Ganser, Arnold, Heineke, Joerg, Heuser, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102189/
https://www.ncbi.nlm.nih.gov/pubmed/32948843
http://dx.doi.org/10.1038/s41375-020-01043-x