Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia

B-cell receptor (BCR) signaling is crucial for the pathophysiology of most mature B-cell lymphomas/leukemias and has emerged as a therapeutic target whose effectiveness remains limited by the occurrence of mutations. Therefore, deciphering the cellular program activated downstream this pathway has b...

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Detalles Bibliográficos
Autores principales: Schleiss, Cedric, Carapito, Raphael, Fornecker, Luc-Matthieu, Muller, Leslie, Paul, Nicodème, Tahar, Ouria, Pichot, Angelique, Tavian, Manuela, Nicolae, Alina, Miguet, Laurent, Mauvieux, Laurent, Herbrecht, Raoul, Cianferani, Sarah, Freund, Jean-Noel, Carapito, Christine, Maumy-Bertrand, Myriam, Bahram, Seiamak, Bertrand, Frederic, Vallat, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102193/
https://www.ncbi.nlm.nih.gov/pubmed/33833385
http://dx.doi.org/10.1038/s41375-021-01221-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102193/
https://www.ncbi.nlm.nih.gov/pubmed/33833385
http://dx.doi.org/10.1038/s41375-021-01221-5

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