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PRDM4 inhibits cell proliferation and tumorigenesis by inactivating the PI3K/AKT signaling pathway through targeting of PTEN in cervical carcinoma

PR domain zinc finger protein 4 (PRDM4) is a transcription factor that plays key roles in stem cell self-renewal and tumorigenesis. However, its biological role and exact mechanism in cervical cancer remain unknown. Here, both immunohistochemistry (IHC) and Western blot assays demonstrated that the...

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Detalles Bibliográficos
Autores principales: Yang, Wen-Ting, Chen, Mei, Xu, Rui, Zheng, Peng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102194/
https://www.ncbi.nlm.nih.gov/pubmed/33846573
http://dx.doi.org/10.1038/s41388-021-01765-x