Menin is necessary for long term maintenance of meningioma-1 driven leukemia

Translocations of Meningioma-1 (MN1) occur in a subset of acute myeloid leukemias (AML) and result in high expression of MN1, either as a full-length protein, or as a fusion protein that includes most of the N-terminus of MN1. High levels of MN1 correlate with poor prognosis. When overexpressed in m...

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Detalles Bibliográficos
Autores principales: Libbrecht, Clara, Xie, Hongbo M., Kingsley, Molly C., Haladyna, Jessica N., Riedel, Simone S., Alikarami, Fatemeh, Lenard, Alexandra, McGeehan, Gerard M., Ernst, Patricia, Bernt, Kathrin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102197/
https://www.ncbi.nlm.nih.gov/pubmed/33542482
http://dx.doi.org/10.1038/s41375-021-01146-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102197/
https://www.ncbi.nlm.nih.gov/pubmed/33542482
http://dx.doi.org/10.1038/s41375-021-01146-z

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