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RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators

Plasma cells (PCs) play an important role in the adaptive immune system through a continuous production of antibodies. We have demonstrated that PC differentiation can be modeled in vitro using complex multistep culture systems reproducing sequential differentiation process occurring in vivo. Here w...

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Detalles Bibliográficos
Autores principales: Kassambara, Alboukadel, Herviou, Laurie, Ovejero, Sara, Jourdan, Michel, Thibaut, Coraline, Vikova, Veronika, Pasero, Philippe, Elemento, Olivier, Moreaux, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102200/
https://www.ncbi.nlm.nih.gov/pubmed/33824465
http://dx.doi.org/10.1038/s41375-021-01234-0