Intoxication of mammalian cells with binary clostridial enterotoxins is inhibited by the combination of pharmacological chaperone inhibitors

Binary enterotoxins Clostridioides difficile CDT toxin, Clostridium botulinum C2 toxin, and Clostridium perfringens iota toxin consist of two separate protein components. The B-components facilitate receptor-mediated uptake into mammalian cells and form pores into endosomal membranes through which t...

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Detalles Bibliográficos
Autores principales: Ernst, Katharina, Sailer, Judith, Braune, Maria, Barth, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102464/
https://www.ncbi.nlm.nih.gov/pubmed/33284399
http://dx.doi.org/10.1007/s00210-020-02029-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102464/
https://www.ncbi.nlm.nih.gov/pubmed/33284399
http://dx.doi.org/10.1007/s00210-020-02029-3

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