MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis

Metastasis-associated protein 2 (MTA2) is a transcription factor that is highly associated with matrix metalloproteinase 12 (MMP12). Thus, we hypothesized that MTA2 may regulate MMP12 expression and is involved in cervical cancer metastasis. Results showed that MTA2 and MMP12 were highly expressed i...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Liang, Ying, Tsung-Ho, Yang, Shun-Fa, Chiou, Hui-Ling, Chen, Yong-Syuan, Kao, Shao-Hsuan, Hsieh, Yi-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102478/
https://www.ncbi.nlm.nih.gov/pubmed/33958583
http://dx.doi.org/10.1038/s41419-021-03729-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102478/
https://www.ncbi.nlm.nih.gov/pubmed/33958583
http://dx.doi.org/10.1038/s41419-021-03729-1

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