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Modeling of stringent-response reflects nutrient stress induced growth impairment and essential amino acids in different Staphylococcus aureus mutants

Stapylococcus aureus colonises the nose of healthy individuals but can also cause a wide range of infections. Amino acid (AA) synthesis and their availability is crucial to adapt to conditions encountered in vivo. Most S. aureus genomes comprise all genes required for AA biosynthesis. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Audretsch, Christof, Gratani, Fabio, Wolz, Christiane, Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102509/
https://www.ncbi.nlm.nih.gov/pubmed/33958641
http://dx.doi.org/10.1038/s41598-021-88646-1