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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4(+) T cell responses

Mast cells are potent mediators of allergy and asthma, yet their role in regulating adaptive immunity remains ambiguous. On the surface of mast cells, the crosslinking of IgE bound to FcεRI by a specific antigen recognized by that IgE triggers the release of immune mediators such as histamine and cy...

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Detalles Bibliográficos
Autores principales: Phong, Binh L., D’Souza, Shaina J., Baudier, Robin L., Wu, Eric, Immethun, Victoria E., Bauer, David L., McLachlan, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102524/
https://www.ncbi.nlm.nih.gov/pubmed/33958642
http://dx.doi.org/10.1038/s41598-021-88956-4