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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4(+) T cell responses
Mast cells are potent mediators of allergy and asthma, yet their role in regulating adaptive immunity remains ambiguous. On the surface of mast cells, the crosslinking of IgE bound to FcεRI by a specific antigen recognized by that IgE triggers the release of immune mediators such as histamine and cy...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102524/ https://www.ncbi.nlm.nih.gov/pubmed/33958642 http://dx.doi.org/10.1038/s41598-021-88956-4 |