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Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies

The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications. Of greatest interest is the ~ 300 amino acid receptor binding domain (RBD) wit...

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Detalles Bibliográficos
Autores principales: Chapman, Asheley P., Tang, Xiaoling, Lee, Joo R., Chida, Asiya, Mercer, Kristina, Wharton, Rebekah E., Kainulainen, Markus, Harcourt, Jennifer L., Martines, Roosecelis B., Schroeder, Michelle, Zhao, Liangjun, Bryksin, Anton, Zhou, Bin, Bergeron, Eric, Bollweg, Brigid C., Tamin, Azaibi, Thornburg, Natalie, Wentworth, David E., Petway, David, Bagarozzi, Dennis A., Finn, M. G., Goldstein, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102525/
https://www.ncbi.nlm.nih.gov/pubmed/33958613
http://dx.doi.org/10.1038/s41598-021-88809-0